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The fact that original research cannot be replicated does not point to fraud, but it does waste resources and slow scientific progress, says Jim Smith of the UK Medical Research Council. He shares his ideas for tackling the problem with Science|Business

Online learning has the potential to reshape education, but a lack of standards and an overwhelming number of apps makes it difficult to identify effective tools, says cognitive science researcher Björn Sjödén. Software developers need to up their game

Irish geneticist David Barton adds his voice to leading research and patient groups across Europe who say proposed new regulations will create unworkable obstacles to DNA testing

To stop publicly-funded research sinking in the valley of death, it is essential to bring industry and universities together in centres dedicated to commercialisation, according to Mike Gregory and Roman Szumski, experts from the UK and Canada

With a government spending review looming, the research lobby is out to make the case for protecting the R&D budget. Here, Hayaatun Sillem of the Royal Academy of Engineering argues an increase in public R&D will pull in more private investment

Brexit would cut research funding and undermine the UK’s standing in science. But more than the money, EU collaboration is needed to address global problems like climate change and ageing, says Cambridge vice chancellor Leszek Borysiewicz

One of the best features of Horizon 2020 risks becoming its fatal flaw. Open-ended competitions have resulted in a flood of doomed applications, some 80 pages in length. Proposals should be shorter, and call topics tightened

German physicist Christiane Heinicke is spending one year as a pretend-astronaut in a Mars simulation. She talks to Science|Business about her motivation for helping to prepare humans mentally for an historic journey to the red planet

His robot can build ‘children’ without human command, but Luzius Brodbeck says it demonstrates that creating truly sophisticated robots is so difficult there is no need to worry about them taking over the world

Despite seeing her text on copyright reform watered down in a European Parliament vote in June, MEP Julia Reda tells Science|Business the case for data mining of published research is too strong for the EU to ignore