Licensing opportunity
Researchers at Edinburgh University, UK, have generated a monoclonal antibody to the streptavidin binding epitope tag, which is widely used in affinity purification of proteins.
Epitope tagging technology has been widely adopted for tagging proteins, as it simplifies the process and makes it easier to detect, purify and assay proteins of interest.
In turn, improved detection enhances studies on function, cellular location, protein to protein interactions, and biochemical activities.
The streptavidin-binding protein monoclonal antibody, raised against the streptavidin binding peptide tag, has been tested in immunoblotting analysis as well as immuno-fluorescence microscopy, and demonstrated to work well. The antibody was raised in mice and is an IgG1k isotype.
The researchers say it would be used as a single antibody for one step purification of interesting proteins. The antibody can be fused to any protein from any species
Edinburgh is looking for an organisation to in-license the antibody and commercialise it for research purposes.
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