Heidelberg: Simplifying systems biology with SYCAMORE

29 Oct 2008 | News

Licensing opportunity

Systems biologists now have a new application that they can use to set up, run and analyse biochemical models – SYCAMORE, developed in Germany. The application, designed to be simpler to use than many modelling software tools currently available, runs via a web browser and is free to use for academic purposes. Commercial users may acquire a licence.

SYCAMORE, SYstems biology Computational Analysis and MOdeling Research Environment, facilitates the construction, simulation and analysis of kinetic models in systems biology. Functions include database-supported modelling, basic model checking, model simulation and the estimation of unknown kinetic parameters based on protein structures.

The application interfaces with other tools such as the COPASI Complex Pathway Simulator, and databases such as BRENDA and SABIO-RK, which contain enzymatic kinetic data. In addition, it offers guidance in order to allow non-expert users to perform basic computational modelling tasks. SYCAMORE is freely available for academic use at http://sycamore.eml.org.

SYCAMORE is a joint project of the Molecular and Cellular Modeling Group and Scientific Databases and Visualization Group at EML Research, as well as the department for Modeling of Biological Processes at the University of Heidelberg. The development of SYCAMORE is supported by the Klaus Tschira Foundation and the German Ministry of Research and Education.

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