Dundee University: First mouse model of psoriasis

Research lead | Licensing opportunity

Researchers at Dundee University have developed the first transgenic mouse model to induce the expression of the PPARδ gene, which is expressed in human psoriatic skin but not in mouse skin.

In the model, the PPARδ gene can be directly activated, and the researchers say the model demonstrates many clinical and histological effects of psoriasis.

The model does not require human skin grafting or implantations, improving the ability of researchers to use the model to screen and simplifying the process of using the model.

The model is suitable for drug screening, removes any need for a skin graft, is simpler to use and demonstrates the major hallmarks of psoriasis.

For more information, visit the project page at http://www.university-technology.com/details/novel-mouse-model-for-research-and-study-of-therapeutic-treatments-in-psoriasis